Targeting the miR-200c/LIN28B axis in acquired EGFR-TKI resistance non-small cell lung cancer cells harboring EMT features

MicroRNA (miR)-200 family members (miR-200s) are frequently silenced in advanced cancer and have been implicated in the process of epithelial-to-mesenchymal transition (EMT). We previously reported that miR-200s were silenced through promoter methylation in acquired EGFR-tyrosine kinase inhibitor (T...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sato, Hiroki, Shien, Kazuhiko, Tomida, Shuta, Okayasu, Kazuhiro, Suzawa, Ken, Hashida, Shinsuke, Torigoe, Hidejiro, Watanabe, Mototsugu, Yamamoto, Hiromasa, Soh, Junichi, Asano, Hiroaki, Tsukuda, Kazunori, Miyoshi, Shinichiro, Toyooka, Shinichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5233972/
https://ncbi.nlm.nih.gov/pubmed/28084458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40847
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