Lipid Geometry and Bilayer Curvature Modulate LC3/GABARAP-Mediated Model Autophagosomal Elongation

Autophagy, an important catabolic pathway involved in a broad spectrum of human diseases, implies the formation of double-membrane-bound structures called autophagosomes (AP), which engulf material to be degraded in lytic compartments. How APs form, especially how the membrane expands and eventually...

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Foilsithe in:Biophys J
Main Authors: Landajuela, Ane, Hervás, Javier H., Antón, Zuriñe, Montes, L. Ruth, Gil, David, Valle, Mikel, Rodriguez, J. Francisco, Goñi, Felix M., Alonso, Alicia
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Biophysical Society 2016
Ábhair:
Membranes
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724631/
https://ncbi.nlm.nih.gov/pubmed/26789764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.11.3524
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