Lipid Geometry and Bilayer Curvature Modulate LC3/GABARAP-Mediated Model Autophagosomal Elongation

Autophagy, an important catabolic pathway involved in a broad spectrum of human diseases, implies the formation of double-membrane-bound structures called autophagosomes (AP), which engulf material to be degraded in lytic compartments. How APs form, especially how the membrane expands and eventually...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biophys J
Prif Awduron: Landajuela, Ane, Hervás, Javier H., Antón, Zuriñe, Montes, L. Ruth, Gil, David, Valle, Mikel, Rodriguez, J. Francisco, Goñi, Felix M., Alonso, Alicia
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2016
Pynciau:
Membranes
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724631/
https://ncbi.nlm.nih.gov/pubmed/26789764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.11.3524
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg