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Novel α-tubulin mutation disrupts neural development and tubulin proteostasis

Mutations in the microtubule cytoskeleton are linked to cognitive and locomotor defects during development, and neurodegeneration in adults. How these mutations impact microtubules, and how this alters function at the level of neurons is an important area of investigation. Using a forward genetic sc...

詳細記述

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書誌詳細
出版年:Dev Biol
主要な著者: Hanson, Martin G., Aiken, Jayne, Sietsema, Daniel V., Sept, David, Bates, Emily A., Niswander, Lee, Moore, Jeffrey K.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724489/
https://ncbi.nlm.nih.gov/pubmed/26658218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2015.11.022
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