miR-508-3p concordantly silences NFKB1 and RELA to inactivate canonical NF-κB signaling in gastric carcinogenesis

BACKGROUND: NF-κB signaling pathway plays an important role in gastric carcinogenesis. The basic expression and functional role of NFKB1 and RELA (components of canonical NF-κB pathway) in gastric cancer (GC) have not been well elucidated. In this study, the role of NFKB1 and RELA in gastric tumorig...

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Vydáno v:Mol Cancer
Hlavní autoři: Huang, Tingting, Kang, Wei, Zhang, Bin, Wu, Feng, Dong, Yujuan, Tong, Joanna H. M., Yang, Weiqin, Zhou, Yuhang, Zhang, Li, Cheng, Alfred S. L., Yu, Jun, To, Ka Fai
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724081/
https://ncbi.nlm.nih.gov/pubmed/26801246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-016-0493-7
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