let-7b/g silencing activates AKT signaling to promote gastric carcinogenesis

BACKGROUND: Aberrant AKT activation contributes to gastric cancer cell survival and chemotherapy resistance, however its regulation is poorly understood. microRNAs have been established to be important regulators in gastric carcinogenesis. Here, we showed the functional role and putative target of l...

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Detalhes bibliográficos
Main Authors: Kang, Wei, Tong, Joanna HM, Lung, Raymond WM, Dong, Yujuan, Yang, Weiqin, Pan, Yi, Lau, Kin Mang, Yu, Jun, Cheng, Alfred SL, To, Ka Fai
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196013/
https://ncbi.nlm.nih.gov/pubmed/25288334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-014-0281-3
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