Targeting of YAP1 by microRNA-15a and microRNA-16-1 exerts tumor suppressor function in gastric adenocarcinoma

BACKGROUND: MicroRNAs (miRNAs) have been reported to play an important role in tumorigenesis. In this study, the role of miR-15a and miR-16-1 in gastric adenocarcinoma (GAC) was investigated. METHODS: The expression of miR-15a and miR-16-1 in cell lines and primary tumors was examined by miRNA qRT-P...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Kang, Wei, Tong, Joanna HM, Lung, Raymond WM, Dong, Yujuan, Zhao, Junhong, Liang, Qiaoyi, Zhang, Li, Pan, Yi, Yang, Weiqin, Pang, Jesse CS, Cheng, Alfred SL, Yu, Jun, To, Ka Fai
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342823/
https://ncbi.nlm.nih.gov/pubmed/25743273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0323-3
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