microRNA-139-5p exerts tumor suppressor function by targeting NOTCH1 in colorectal cancer

BACKGROUND: miR-139-5p was identified to be significantly down-regulated in colon tumor tissues by miRNA array. We aimed to clarify its biological function, molecular mechanisms and direct target gene in colorectal cancer (CRC). METHODS: The biological function of miR-139-5p was examined by cell gro...

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Detalhes bibliográficos
Main Authors: Zhang, Lijing, Dong, Yujuan, Zhu, Nana, Tsoi, Ho, Zhao, Zengren, Wu, Chung Wah, Wang, Kunning, Zheng, Shu, Ng, Simon SM, Chan, Francis KL, Sung, Joseph JY, Yu, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065091/
https://ncbi.nlm.nih.gov/pubmed/24885920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-124
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