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Sorafenib in combination with low-dose-homoharringtonine as a salvage therapy in primary refractory FLT3-ITD-positive AML: a case report and review of literature

The presence of internal tandem duplications (ITD) in the Fms-related tyrosine kinase 3 receptor (FLT3) has been associated with a poor prognosis in acute myeloid leukemia (AML). Over the past decade, FLT3 is a promising target in FLT3-ITD-positive AML. Sorafenib which is one of the commonly focused...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Med
Main Authors: Xu, Gaixiang, Mao, Liping, Liu, Hui, Yang, Min, Jin, Jie, Qian, Wenbin
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4723746/
https://ncbi.nlm.nih.gov/pubmed/26884901
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