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A Viral microRNA Cluster Regulates the Expression of PTEN, p27 and of a bcl-2 Homolog
The Epstein-Barr virus (EBV) infects and transforms B-lymphocytes with high efficiency. This process requires expression of the viral latent proteins and of the 3 miR-BHRF1 microRNAs. Here we show that B-cells infected by a virus that lacks these non-coding RNAs (Δ123) grew more slowly between day 5...
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| Veröffentlicht in: | PLoS Pathog |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4723338/ https://ncbi.nlm.nih.gov/pubmed/26800049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005405 |
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