Spontaneous lymphoblastoid cell lines from patients with Epstein-Barr virus infection show highly variable proliferation characteristics that correlate with the expression levels of viral microRNAs

The Epstein-Barr virus (EBV) induces B-cell proliferation with high efficiency through expression of latent proteins and microRNAs. This process takes place in vivo soon after infection, presumably to expand the virus reservoir, but can also induce pathologies, e.g. an infectious mononucleosis (IM)...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Delecluse, Susanne, Yu, Jiyang, Bernhardt, Katharina, Haar, Janina, Poirey, Remy, Tsai, Ming-Han, Kiblawi, Rama, Kopp-Schneider, Annette, Schnitzler, Paul, Zeier, Martin, Dreger, Peter, Wuchter, Patrick, Bulut, Olcay Cem, Behrends, Uta, Delecluse, Henri-Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768455/
https://ncbi.nlm.nih.gov/pubmed/31568538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0222847
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