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Spatial Metrics of Tumour Vascular Organisation Predict Radiation Efficacy in a Computational Model

Intratumoural heterogeneity is known to contribute to poor therapeutic response. Variations in oxygen tension in particular have been correlated with changes in radiation response in vitro and at the clinical scale with overall survival. Heterogeneity at the microscopic scale in tumour blood vessel...

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Bibliografiska uppgifter
I publikationen:PLoS Comput Biol
Huvudupphovsmän: Scott, Jacob G., Fletcher, Alexander G., Anderson, Alexander R. A., Maini, Philip K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4723304/
https://ncbi.nlm.nih.gov/pubmed/26800503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004712
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