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Inferring Tumor Proliferative Organization from Phylogenetic Tree Measures in a Computational Model
We use a computational modeling approach to explore whether it is possible to infer a solid tumor’s cellular proliferative hierarchy under the assumptions of the cancer stem cell hypothesis and neutral evolution. We work towards inferring the symmetric division probability for cancer stem cells, sin...
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| Publicat a: | Syst Biol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7302056/ https://ncbi.nlm.nih.gov/pubmed/31665523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/sysbio/syz070 |
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