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Spatial Metrics of Tumour Vascular Organisation Predict Radiation Efficacy in a Computational Model

Intratumoural heterogeneity is known to contribute to poor therapeutic response. Variations in oxygen tension in particular have been correlated with changes in radiation response in vitro and at the clinical scale with overall survival. Heterogeneity at the microscopic scale in tumour blood vessel...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Scott, Jacob G., Fletcher, Alexander G., Anderson, Alexander R. A., Maini, Philip K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4723304/
https://ncbi.nlm.nih.gov/pubmed/26800503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004712
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