Molecular Dissection of Induced Platinum Resistance through Functional and Gene Expression Analysis in a Cell Culture Model of Bladder Cancer

We report herein the development, functional and molecular characterization of an isogenic, paired bladder cancer cell culture model system for studying platinum drug resistance. The 5637 human bladder cancer cell line was cultured over ten months with stepwise increases in oxaliplatin concentration...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Wang, Sisi, Zhang, Hongyong, Scharadin, Tiffany M., Zimmermann, Maike, Hu, Bin, Pan, Amy Wang, Vinall, Ruth, Lin, Tzu-yin, Cimino, George, Chain, Patrick, Vuyisich, Momchilo, Gleasner, Cheryl, Mcmurry, Kim, Malfatti, Michael, Turteltaub, Kenneth, de Vere White, Ralph, Pan, Chong-xian, Henderson, Paul T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4723083/
https://ncbi.nlm.nih.gov/pubmed/26799320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146256
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