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Sensitivity of K(ATP) channels to cellular metabolic disorders and the underlying structural basis

AIM: ATP-sensitive potassium (K(ATP)) channels formed by a combination of SUR/Kir6.x subunits play a crucial role in protection against hypoxic or ischemic injuries resulting from cell metabolic disorders. In this study we investigated the effects of Na-azide, a metabolic inhibitor, on K(ATP) channe...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Li, Chun-gang, Cui, Wen-yu, Wang, Hai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4722982/
https://ncbi.nlm.nih.gov/pubmed/26725741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.134
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