Molecular Basis and Structural Insight of Vascular K(ATP) Channel Gating by S-Glutathionylation

The vascular ATP-sensitive K(+) (K(ATP)) channel is targeted by a variety of vasoactive substances, playing an important role in vascular tone regulation. Our recent studies indicate that the vascular K(ATP) channel is inhibited in oxidative stress via S-glutathionylation. Here we show evidence for...

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Detalhes bibliográficos
Main Authors: Yang, Yang, Shi, Weiwei, Chen, Xianfeng, Cui, Ningren, Konduru, Anuhya S., Shi, Yun, Trower, Timothy C., Zhang, Shuang, Jiang, Chun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Membrane Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059003/
https://ncbi.nlm.nih.gov/pubmed/21216949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.195123
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