EFNA3 long noncoding RNAs induced by hypoxia promote metastatic dissemination

The presence of hypoxic regions in solid tumors is an adverse prognostic factor for patient outcome. Here, we show that hypoxia induces the expression of Ephrin-A3 through a novel hypoxia-inducible factor (HIF)-mediated mechanism. In response to hypoxia, the coding EFNA3 mRNA levels remained relativ...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Gómez-Maldonado, L, Tiana, M, Roche, O, Prado-Cabrero, A, Jensen, L, Fernandez-Barral, A, Guijarro-Muñoz, I, Favaro, E, Moreno-Bueno, G, Sanz, L, Aragones, J, Harris, A, Volpert, O, Jimenez, B, del Peso, L
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4722872/
https://ncbi.nlm.nih.gov/pubmed/25023702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.200
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