The cell surface mucin podocalyxin regulates collective breast tumor budding

BACKGROUND: Overexpression of the transmembrane sialomucin podocalyxin, which is known to play a role in lumen formation during polarized epithelial morphogenesis, is an independent indicator of poor prognosis in a number of epithelial cancers, including those that arise in the breast. Therefore, we...

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Publicat a:Breast Cancer Res
Autors principals: Graves, Marcia L., Cipollone, Jane A., Austin, Pamela, Bell, Erin M., Nielsen, Julie S., Gilks, C. Blake, McNagny, Kelly M., Roskelley, Calvin D.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4722710/
https://ncbi.nlm.nih.gov/pubmed/26796961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-015-0670-4
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