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Clinical evaluation of panel testing by next-generation sequencing (NGS) for gene mutations in myeloid neoplasms

BACKGROUND: Genomic techniques in recent years have allowed the identification of many mutated genes important in the pathogenesis of acute myeloid leukemia (AML). Together with cytogenetic aberrations, these gene mutations are powerful prognostic markers in AML and can be used to guide patient mana...

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Bibliografske podrobnosti
izdano v:Diagn Pathol
Main Authors: Au, Chun Hang, Wa, Anna, Ho, Dona N., Chan, Tsun Leung, Ma, Edmond S. K.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4722624/
https://ncbi.nlm.nih.gov/pubmed/26796102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-016-0456-8
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