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The effect of 5-fluorouracil/leucovorin chemotherapy on CpG methylation, or the confounding role of leukocyte heterogeneity: an illustration

Blood-based epigenome-wide association studies that aim at comparing CpG methylation between colorectal cancer (CRC) patients and controls can lead to the discovery of diagnostic or prognostic biomarkers. Numerous confounders can lead to spurious associations. We aimed to see if 5-fluorouracil (5-FU...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Genomics
Egile Nagusiak: Lemire, Mathieu, Zaidi, Syed H.E., Zanke, Brent W., Gallinger, Steven, Hudson, Thomas J., Cleary, Sean P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4722538/
https://ncbi.nlm.nih.gov/pubmed/26368860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2015.09.003
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