Loss of G(s)α in the Postnatal Skeleton Leads to Low Bone Mass and a Blunted Response to Anabolic Parathyroid Hormone Therapy

Parathyroid hormone (PTH) is an important regulator of osteoblast function and is the only anabolic therapy currently approved for treatment of osteoporosis. The PTH receptor (PTH1R) is a G protein-coupled receptor that signals via multiple G proteins including G(s)α. Mice expressing a constitutivel...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sinha, Partha, Aarnisalo, Piia, Chubb, Rhiannon, Poulton, Ingrid J., Guo, Jun, Nachtrab, Gregory, Kimura, Takaharu, Swami, Srilatha, Saeed, Hamid, Chen, Min, Weinstein, Lee S., Schipani, Ernestina, Sims, Natalie A., Kronenberg, Henry M., Wu, Joy Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4722446/
https://ncbi.nlm.nih.gov/pubmed/26598522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.679753
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados