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DECREASED OXIDATIVE STRESS AND GREATER BONE ANABOLISM IN THE AGED, AS COMPARED TO THE YOUNG, MURINE SKELETON BY PARATHYROID HORMONE

Because of recent insights into the pathogenesis of age-related bone loss, we investigated whether intermittent parathyroid hormone (PTH) administration antagonizes the molecular mechanisms of the adverse effects of aging on bone. PTH produced a greater increase in vertebral trabecular bone mineral...

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Detalhes bibliográficos
Main Authors: Jilka, R.L., Almeida, M., Ambrogini, E., Han, L., Roberson, P. K., Weinstein, R.S., Manolagas, S.C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958819/
https://ncbi.nlm.nih.gov/pubmed/20698835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2010.00616.x
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