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Remote control of therapeutic T cells through a small molecule-gated chimeric receptor
There is growing promise in using engineered cells as therapeutic agents. For example, synthetic Chimeric Antigen Receptors (CARs) can redirect T cells to recognize and eliminate tumor cells expressing specific antigens. Despite promising clinical results, excessive activity and poor control over su...
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| Опубликовано в: : | Science |
|---|---|
| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4721629/ https://ncbi.nlm.nih.gov/pubmed/26405231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aab4077 |
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