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Atg7 Modulates p53 Activity to Regulate Cell Cycle and Survival During Metabolic Stress

Withdrawal of nutrients triggers an exit from the cell division cycle, the induction of autophagy, and eventually the activation of cell death pathways. The relation, if any, among these events is not well characterized. We found that starved mouse embryonic fibroblasts lacking the essential autopha...

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Bibliografiske detaljer
Udgivet i:Science
Main Authors: Lee, In Hye, Kawai, Yoshichika, Fergusson, Maria M., Rovira, Ilsa I., Bishop, Alexander J. R., Motoyama, Noboru, Cao, Liu, Finkel, Toren
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4721513/
https://ncbi.nlm.nih.gov/pubmed/22499945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1218395
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