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Atg7 Modulates p53 Activity to Regulate Cell Cycle and Survival During Metabolic Stress

Withdrawal of nutrients triggers an exit from the cell division cycle, the induction of autophagy, and eventually the activation of cell death pathways. The relation, if any, among these events is not well characterized. We found that starved mouse embryonic fibroblasts lacking the essential autopha...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Lee, In Hye, Kawai, Yoshichika, Fergusson, Maria M., Rovira, Ilsa I., Bishop, Alexander J. R., Motoyama, Noboru, Cao, Liu, Finkel, Toren
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4721513/
https://ncbi.nlm.nih.gov/pubmed/22499945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1218395
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