The Essential Autophagy Gene ATG7 Modulates Organ Fibrosis via Regulation of Endothelial-to-Mesenchymal Transition

Pulmonary fibrosis is a progressive disease characterized by fibroblast proliferation and excess deposition of collagen and other extracellular matrix components. Although the origin of fibroblasts is multifactorial, recent data implicate endothelial-to-mesenchymal transition as an important source...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Singh, Krishna K., Lovren, Fina, Pan, Yi, Quan, Adrian, Ramadan, Azza, Matkar, Pratiek N., Ehsan, Mehroz, Sandhu, Paul, Mantella, Laura E., Gupta, Nandini, Teoh, Hwee, Parotto, Matteo, Tabuchi, Arata, Kuebler, Wolfgang M., Al-Omran, Mohammed, Finkel, Toren, Verma, Subodh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317030/
https://ncbi.nlm.nih.gov/pubmed/25527499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.604603
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