The Essential Autophagy Gene ATG7 Modulates Organ Fibrosis via Regulation of Endothelial-to-Mesenchymal Transition

Pulmonary fibrosis is a progressive disease characterized by fibroblast proliferation and excess deposition of collagen and other extracellular matrix components. Although the origin of fibroblasts is multifactorial, recent data implicate endothelial-to-mesenchymal transition as an important source...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Singh, Krishna K., Lovren, Fina, Pan, Yi, Quan, Adrian, Ramadan, Azza, Matkar, Pratiek N., Ehsan, Mehroz, Sandhu, Paul, Mantella, Laura E., Gupta, Nandini, Teoh, Hwee, Parotto, Matteo, Tabuchi, Arata, Kuebler, Wolfgang M., Al-Omran, Mohammed, Finkel, Toren, Verma, Subodh
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Molecular Bases of Disease
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317030/
https://ncbi.nlm.nih.gov/pubmed/25527499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.604603
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