Microglial Hv1 proton channel promotes cuprizone-induced demyelination through oxidative damage

NADPH oxidase (NOX)-dependent reactive oxygen species (ROS) production in inflammatory cells including microglia plays an important role in demyelination and free radical-mediated tissue injury in multiple sclerosis (MS). However, the mechanism underlying microglial ROS production and demyelination...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Neurochem
Main Authors: Liu, Junli, Tian, Daishi, Murugan, Madhuvika, Eyo, Ukpong B., Dreyfus, Cheryl F., Wang, Wei, Wu, Long-Jun
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4721248/
https://ncbi.nlm.nih.gov/pubmed/26173779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13242
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