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Microglial Hv1 proton channel promotes cuprizone-induced demyelination through oxidative damage
NADPH oxidase (NOX)-dependent reactive oxygen species (ROS) production in inflammatory cells including microglia plays an important role in demyelination and free radical-mediated tissue injury in multiple sclerosis (MS). However, the mechanism underlying microglial ROS production and demyelination...
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| Publicado en: | J Neurochem |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4721248/ https://ncbi.nlm.nih.gov/pubmed/26173779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13242 |
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