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Comparisons of biophysical properties and bioactivities of mono-PEGylated endostatin and an endostatin analog
BACKGROUND: Endostatin (ES) is a well-established potent endogenous antiangiogenic factor. An ES variant, called zinc-binding protein-ES (ZBP-ES), is clinically available; however, its use is limited by rapid renal clearance and short residence time. PEGylation has been exploited to overcome these s...
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| Publicado no: | Chin J Cancer |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4721152/ https://ncbi.nlm.nih.gov/pubmed/26792627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40880-016-0080-8 |
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