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Transcriptional enhancers: functional insights and role in human disease

In recent years, studies of cis-regulatory mechanisms have evolved from a predominant focus on promoter regions to the realization that spatial and temporal gene regulation is frequently driven by long-range enhancer clusters that operate within chromosomal compartments. This increased understanding...

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Detalhes bibliográficos
Publicado no:Curr Opin Genet Dev
Main Authors: Miguel-Escalada, Irene, Pasquali, Lorenzo, Ferrer, Jorge
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720706/
https://ncbi.nlm.nih.gov/pubmed/26433090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2015.08.009
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