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A PDZ-Like Motif in the Biliary Transporter ABCB4 Interacts with the Scaffold Protein EBP50 and Regulates ABCB4 Cell Surface Expression

ABCB4/MDR3, a member of the ABC superfamily, is an ATP-dependent phosphatidylcholine translocator expressed at the canalicular membrane of hepatocytes. Defects in the ABCB4 gene are associated with rare biliary diseases. It is essential to understand the mechanisms of its canalicular membrane expres...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Venot, Quitterie, Delaunay, Jean-Louis, Fouassier, Laura, Delautier, Danièle, Falguières, Thomas, Housset, Chantal, Maurice, Michèle, Aït-Slimane, Tounsia
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720445/
https://ncbi.nlm.nih.gov/pubmed/26789121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146962
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