Structural Mechanism behind Distinct Efficiency of Oct4/Sox2 Proteins in Differentially Spaced DNA Complexes

The octamer-binding transcription factor 4 (Oct4) and sex-determining region Y (SRY)-box 2 (Sox2) proteins induce various transcriptional regulators to maintain cellular pluripotency. Most Oct4/Sox2 complexes have either 0 base pairs (Oct4/Sox2(0bp)) or 3 base pairs (Oct4/Sox2(3bp)) separation betwe...

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Bibliographic Details
Published in:PLoS One
Main Authors: Yesudhas, Dhanusha, Anwar, Muhammad Ayaz, Panneerselvam, Suresh, Durai, Prasannavenkatesh, Shah, Masaud, Choi, Sangdun
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720428/
https://ncbi.nlm.nih.gov/pubmed/26790000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147240
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