A Combined Molecular Docking/Dynamics Approach to Probe the Binding Mode of Cancer Drugs with Cytochrome P450 3A4

Cytarabine, daunorubicin, doxorubicin and vincristine are clinically used for combinatorial therapies of cancers in different combinations. However, the knowledge about the interaction of these drugs with the metabolizing enzyme cytochrome P450 is limited. Therefore, we utilized computational method...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Panneerselvam, Suresh, Yesudhas, Dhanusha, Durai, Prasannavenkatesh, Anwar, Muhammad Ayaz, Gosu, Vijayakumar, Choi, Sangdun
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6332164/
https://ncbi.nlm.nih.gov/pubmed/26287147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules200814915
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