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Evaluation of Sox2 binding affinities for distinct DNA patterns using steered molecular dynamics simulation
Transcription factors (TFs) are gene expression regulators that bind to DNA in a sequence‐specific manner and determine the functional characteristics of the gene. It is worthwhile to study the unique characteristics of such specific TF‐binding pattern in DNA. Sox2 recognizes a 6‐ to 7‐base pair con...
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| Publicado no: | FEBS Open Bio |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5666385/ https://ncbi.nlm.nih.gov/pubmed/29123983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12316 |
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