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Detection of low-abundance bacterial strains in metagenomic datasets by eigengenome partitioning

Analyses of metagenomic datasets that are sequenced to a depth of billions or trillions of bases can uncover hundreds of microbial genomes, but naive assembly of these data is computationally intensive, requiring hundreds of gigabytes to terabytes of RAM. This is a bottleneck in many studies, especi...

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Bibliografski detalji
Izdano u:Nat Biotechnol
Glavni autori: Cleary, Brian, Brito, Ilana Lauren, Huang, Katherine, Gevers, Dirk, Shea, Terrance, Young, Sarah, Alm, Eric
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720164/
https://ncbi.nlm.nih.gov/pubmed/26368049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3329
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