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Detection of low-abundance bacterial strains in metagenomic datasets by eigengenome partitioning

Analyses of metagenomic datasets that are sequenced to a depth of billions or trillions of bases can uncover hundreds of microbial genomes, but naive assembly of these data is computationally intensive, requiring hundreds of gigabytes to terabytes of RAM. This is a bottleneck in many studies, especi...

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Detalhes bibliográficos
Publicado no:Nat Biotechnol
Main Authors: Cleary, Brian, Brito, Ilana Lauren, Huang, Katherine, Gevers, Dirk, Shea, Terrance, Young, Sarah, Alm, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720164/
https://ncbi.nlm.nih.gov/pubmed/26368049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3329
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