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Detection of low-abundance bacterial strains in metagenomic datasets by eigengenome partitioning
Analyses of metagenomic datasets that are sequenced to a depth of billions or trillions of bases can uncover hundreds of microbial genomes, but naive assembly of these data is computationally intensive, requiring hundreds of gigabytes to terabytes of RAM. This is a bottleneck in many studies, especi...
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Publicado no: | Nat Biotechnol |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4720164/ https://ncbi.nlm.nih.gov/pubmed/26368049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3329 |
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