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Detection of low-abundance bacterial strains in metagenomic datasets by eigengenome partitioning

Analyses of metagenomic datasets that are sequenced to a depth of billions or trillions of bases can uncover hundreds of microbial genomes, but naive assembly of these data is computationally intensive, requiring hundreds of gigabytes to terabytes of RAM. This is a bottleneck in many studies, especi...

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Bibliografiska uppgifter
I publikationen:Nat Biotechnol
Huvudupphovsmän: Cleary, Brian, Brito, Ilana Lauren, Huang, Katherine, Gevers, Dirk, Shea, Terrance, Young, Sarah, Alm, Eric
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720164/
https://ncbi.nlm.nih.gov/pubmed/26368049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3329
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