Genome-wide12 DNA methylation profiling in the superior temporal gyrus reveals epigenetic signatures associated with Alzheimer’s disease

BACKGROUND: Alzheimer’s disease affects ~13 % of people in the United States 65 years and older, making it the most common neurodegenerative disorder. Recent work has identified roles for environmental, genetic, and epigenetic factors in Alzheimer’s disease risk. METHODS: We performed a genome-wide...

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Watson, Corey T., Roussos, Panos, Garg, Paras, Ho, Daniel J., Azam, Nidha, Katsel, Pavel L., Haroutunian, Vahram, Sharp, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719699/
https://ncbi.nlm.nih.gov/pubmed/26803900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0258-8
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