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The triggering receptor expressed on myeloid cells 2 (TREM2) is associated with enhanced inflammation, neuropathological lesions and increased risk for Alzheimer’s Dementia

OBJECTIVE: To elucidate the relationship between the triggering receptor expressed on myeloid cells 2 (TREM2) risk variant, neuropathological lesions, alterations in gene and protein expression and severity of neuroinflammation. METHODS: Genetic association study of the R47H TREM2 variant with Alzhe...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement
Main Authors: Roussos, Panos, Katsel, Pavel, Fam, Peter, Tan, Weilun, Purohit, Dushyant P., Haroutunian, Vahram
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461564/
https://ncbi.nlm.nih.gov/pubmed/25499537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2014.10.013
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