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Noncanonical NF-κB Activation Mediates STAT3-stimulated IDO Upregulation in Myeloid-Derived Suppressor Cells in Breast Cancer

Immunotherapy exerts anticancer effects by activating competent immune effectors and inhibiting immunosuppressive cells, such as myeloid-derived suppressor cells (MDSCs). However, the mechanism underlying MDSCs-mediated immunosuppression in breast cancer is unclear. We have identified a poorly diffe...

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Detalles Bibliográficos
Publicado en:J Immunol
Autores principales: Yu, Jinpu, Wang, Yue, Yan, Fang, Zhang, Peng, Li, Hui, Zhao, Hua, Yan, Cihui, Yan, Fan, Ren, Xiubao
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719564/
https://ncbi.nlm.nih.gov/pubmed/25063873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400833
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