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The tumor suppressor gene WWOX links the canonical and noncanonical NF-κB pathways in HTLV-I Tax-mediated tumorigenesis

Both the canonical and noncanonical nuclear factor κB (NF-κB) pathways have been linked to tumorigenesis. However, it remains unknown whether and how the 2 signaling pathways cooperate during tumorigenesis. We report that inhibition of the noncanonical NF-κB pathway significantly delays tumorigenesi...

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Hlavní autoři: Fu, Jing, Qu, Zhaoxia, Yan, Pengrong, Ishikawa, Chie, Aqeilan, Rami I., Rabson, Arnold B., Xiao, Gutian
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318777/
https://ncbi.nlm.nih.gov/pubmed/21115974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-08-303073
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