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GroEL2 of Mycobacterium tuberculosis Reveals the Importance of Structural Pliability in Chaperonin Function

Intracellular protein folding is mediated by molecular chaperones, the best studied among which are the chaperonins GroEL and GroES. Conformational changes and allosteric transitions between different metastable states are hallmarks of the chaperonin mechanism. These conformational transitions betwe...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Bacteriol
Main Authors: Chilukoti, Neeraja, Kumar, C. M. Santosh, Mande, Shekhar C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719451/
https://ncbi.nlm.nih.gov/pubmed/26553853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00844-15
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