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The Mediator Subunit MED16 Transduces NRF2-Activating Signals into Antioxidant Gene Expression
The KEAP1-NRF2 system plays a central role in cytoprotection. NRF2 is stabilized in response to electrophiles and activates transcription of antioxidant genes. Although robust induction of NRF2 target genes confers resistance to oxidative insults, how NRF2 triggers transcriptional activation after b...
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| Publicado en: | Mol Cell Biol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4719425/ https://ncbi.nlm.nih.gov/pubmed/26572828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00785-15 |
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