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High Fractional Occupancy of a Tandem Maf Recognition Element and Its Role in Long-Range β-Globin Gene Regulation

Enhancers and promoters assemble protein complexes that ultimately regulate the recruitment and activity of RNA polymerases. Previous work has shown that at least some enhancers form stable protein complexes, leading to the formation of enhanceosomes. We analyzed protein-DNA interactions in the muri...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Stees, Jared R., Hossain, Mir A., Sunose, Tomoki, Kudo, Yasushi, Pardo, Carolina E., Nabilsi, Nancy H., Darst, Russell P., Poudyal, Rosha, Igarashi, Kazuhiko, Huang, Suming, Kladde, Michael P., Bungert, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719303/
https://ncbi.nlm.nih.gov/pubmed/26503787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00723-15
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