Myosin IXa Binds AMPAR and Regulates Synaptic Structure, LTP, and Cognitive Function

Myosin IXa (Myo9a) is a motor protein that is highly expressed in the brain. However, the role of Myo9a in neurons remains unknown. Here, we investigated Myo9a function in hippocampal synapses. In rat hippocampal neurons, Myo9a localizes to the postsynaptic density (PSD) and binds the alpha-amino-3-...

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Vydáno v:Front Mol Neurosci
Hlavní autoři: Folci, Alessandra, Murru, Luca, Vezzoli, Elena, Ponzoni, Luisa, Gerosa, Laura, Moretto, Edoardo, Longo, Fabiana, Zapata, Jonathan, Braida, Daniela, Pistillo, Francesco, Bähler, Martin, Francolini, Maura, Sala, Mariaelvina, Bassani, Silvia
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2016
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719083/
https://ncbi.nlm.nih.gov/pubmed/26834556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00001
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