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Myosin IXa Regulates Epithelial Differentiation and Its Deficiency Results in Hydrocephalus
The ependymal multiciliated epithelium in the brain restricts the cerebrospinal fluid to the cerebral ventricles and regulates its flow. We report here that mice deficient for myosin IXa (Myo9a), an actin-dependent motor molecule with a Rho GTPase–activating (GAP) domain, develop severe hydrocephalu...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2793285/ https://ncbi.nlm.nih.gov/pubmed/19828736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-04-0291 |
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