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Striking HIV-1 Entry by Targeting HIV-1 gp41. But, Where Should We Target?

HIV-1 gp41 facilitates the viral fusion through a conformational switch involving the association of three C-terminal helices along the conserved hydrophobic grooves of three N-terminal helices coiled-coil. The control of these structural rearrangements is thought to be central to HIV-1 entry and, t...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Teixeira, Cátia, Barbault, Florent, Couesnon, Thierry, Gomes, José R. B., Gomes, Paula, Maurel, François
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718650/
https://ncbi.nlm.nih.gov/pubmed/26785380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146743
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