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Approaches for Identification of HIV-1 Entry Inhibitors Targeting gp41 Pocket
The hydrophobic pocket in the HIV-1 gp41 N-terminal heptad repeat (NHR) domain plays an important role in viral fusion and entry into the host cell, and serves as an attractive target for development of HIV-1 fusion/entry inhibitors. The peptide anti-HIV drug targeting gp41 NHR, T-20 (generic name:...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3564113/ https://ncbi.nlm.nih.gov/pubmed/23344560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v5010127 |
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