ANTIBACTERIAL PROPERTIES OF THE CFTR POTENTIATOR IVACAFTOR

BACKGROUND: Ivacaftor increases CFTR channel activity and improves pulmonary function for individuals bearing a G551D mutation. Because ivacaftor structurally resembles quinolone antibiotics, we tested the hypothesis that ivacaftor possesses antibacterial properties. METHODS: Bioluminescence, colony...

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Bibliografski detalji
Izdano u:J Cyst Fibros
Glavni autori: Reznikov, Leah R., Abou Alaiwa, Mahmoud H., Dohrn, Cassie L., Gansemer, Nick D., Diekema, Daniel J., Stoltz, David A., Welsh, Michael J.
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718582/
https://ncbi.nlm.nih.gov/pubmed/24618508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcf.2014.02.004
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